Eden Materials

Flexdym Starter Pack - Alternative To PDMS

The Flexdym starter pack is great for first time users. Each pack contains 10 sheets of 15 x 15 cm Flexdym sheets, which can be selected from any one of our 4 thicknesses: 250 µm, 750 µm, 1200 µm and 2000 µm. And different thicknesses can be mixed in one pack!

Clear
SKU: M-FS Category:

Are you looking for an alternative to PDMS soft-lithography for your microfluidics applications? The Flexdym polymer is an increasingly popular alternative to PDMS and the first material specifically tailored for microfluidics chip fabrication. Why? Because while developing Flexdym, we seriously considered the needs of microfluidic biotech applications. Firstly, Flexdym is certified biocompatible according to international codes ISO 10993 (parts 4, 5, 6, 10, 11) and UPS Class VI. So that you can use it for the most important biological applications, such as organ-on-chip and point of care diagnostics. But this wouldn’t be enough. So we also made sure Flexdym has optical transparency, low molecular sorption properties and reduced gas permeability.

 Flexdym is a pressure-sensitive adhesive (PSA), which can bond to a variety of substrates including COC, COP, PS, PC, PMMA, and PDMS – to name a few. This provides a large range of versatility, according to the application at hand. The bonding strength varies according to the substrate, providing the option over reversible and permanent bonding. For this reason, Flexdym serves as an excellent option for skin-interfaced microfluidic devices or for reversible sealing of microfluidic cartridges.

Another major advantage of using Flexdym as an alternative to PDMS, is that Flexdym can be used in the scale up of microfluidics chips for commercial or industrial purposes. The starter pack is the perfect format for first-time Flexdym users to test the material for their  application. In one starter pack different thicknesses can be mixed, making the selection process easier for you! Once you have discovered your thickness of choice, the next step is to scale-up with our more cost effective formats, linked here: Flexdym Rolls or Flexdym Pellets.

Remember you can follow Eden Tech on Linkedin, to get all our current news!

Thickness

250µm, 750µm, 1200µm, 2000µm, Mixed Pack

Size

15 cm x 15 cm

Hardness Shore A

35

Specific gravity

0.9 g/cm3

Tear strength

15 kN/m

Tensile strength

7.6 kN/m

Elongation

720%

Molding temperature

115 – 185 °C

Molding pressure

35 Torr

Create Flexdym Microfluidic Devices in Minutes

Looking to Test Out Flexdym?

Flexdym sheets image orange | Eden Tech

The starter pack contains 10 sheets of 15 x 15 cm Flexdym, wrapped in 2 protective transparent films.

Flexdym Sheet Thickness orange | Eden Tech

In one pack you have the choice to include a range of different thicknesses: 0.25 mm, 0.75 mm, 1.2 mm or 2 mm. You can also mix these according to your preference.

Flexdym microfluidic device image orangeFlexdym roll orange | Eden Tech

Each sheet can be cut using scissors & molded using a hot press. Depending on the size of the mold, the process can last from 1 to 15 minutes.

Flexdym Handling

A Flexdym sheet is protected with films on either side, to avoid contamination of the material by dust particles or other substances. Keep the protective films on the sheet when cutting (using scissors or die cut). Remove the films once you are ready to sandwich your Flexdym sheet between your mold and counter mold. 

Flexdym handling instructionsFlexdym microfluidic device image orangeFlexdym roll orange | Eden Tech

Step-by-Step:
Flexdym Devices

01

Cut Flexdym Sheet Sketch orange Flexdym microfluidic device image orangeFlexdym roll orange | Eden Tech

Cut a Flexdym sheet

02

Mold Flexdym Sheet Sketch orange | Eden Tech

Mold within 2 minutes

03

Flexdym Create Inlets and Outlets Sketch Orange | Eden Tech

Create inlet/outlet ports

04

Flexdym Device Ready Sketch Orange | Eden Tech

Bond Flexdym to substrate

A Biocompatible Material that is Scalable.

Flexdym at Different scales | Eden Tech

From Prototyping...

Use Flexdym starter packs or rolls to create chips quickly and easily. Mold Flexdym in 2 minutes using our Sublym machine. The Flexdym protocol length is approx. 15-20 minutes, so you can save time in the lab.

...to Mass Production.

The Flexdym pellets are compatible with injection molding machines used in mass production. Now you have the opportunity to turn you technology into a commercial product.

Molding Flexdym:
The Sublym Machine vs. A Hot Press

Eden Tech’s mission is to create user-friendly microfabrication solutions to help researchers boost chip production. With the creation of Flexdym, it was important to offer an affordable machine to mold the material.

Flexdym’s thermoplastic properties means it can be molded via hot embossing, just like other thermoplastics (e.g. COC, polystyrene, or polycarbonate). Hot embossing involves utlizing pressure, heat and  time to transfer features from the mold to the material. Hot embossing is a great alternative to casting and soft-lithgraphy methods of microfabrication.

Explore below 2 methods of hot embossing: 

Sublym hot embossing machine GIF

Sublym100 Machine

1

Optimized for Flexdym molding in only 1-2 minutes!

2

Compact & User-friendly design that requires little to no training.

3

Dramatically cheaper than most standard clean room equipment. This small investment is an opportunity for you to begin exploring microfluidics.

Classic Hot Press

1

Not optimized for Flexdym molding, therefore longer  molding time.

2

Less easy to use alternative for the Sublym100.

3

Slightly more expensive than the Sublym100, but a standard piece of equipment which is generally installed in fabrication facilities.

Molds For Hot Embossing

Expoxy-resin mold | Eden Tech

Epoxy Resin Mold

Epoxy resin molds are one of the best options for hot embossing. They remain robust through repeated molding cycles. Our Epoxym kit enables the fabrication of epoxy mold replicas from Silicon wafers.

Glass Mold

Glass Mold

Etched glass molds are another robust option for hot embossing. 

Metal Mold

Metal Mold

Metal molds, such as those made from aluminium, are a good option. 

Silicon Wafer

Silicon Wafer

The least ideal option for hot embossing are SU-8 & silicon wafers, due to their fragility and ease of breakage. However, when carefully handled and coated with non-stick spray, they do the trick. 

Flexdym Pricing

Eden Tech has optimized Flexdym’s pricing to be comparable to other widely used microfabrication materials, with the added advantages of being:

Biocompatible

Transparent

Scalable

User-Friendly

Versatility: Flexdym Bonding Strength

Flexdym combines the best properties of elastomers, like PDMS, and thermoplastics, like COC, polystyrene or polycarbonate. Flexdym acheives this through its block co-polymer structure composed of styrenic hard blocks and ethylene-butylene soft blocks, which allow it to remain soft, yet compatible with hot embossing.

Flexdym acts as a pressure sensitive adhesive, bonding with a selection of substrates through conformal contact. Flexdym bonding can be accomplished through manual lamination using a roller, or standardised through the use of a press.

Flexdym can be recycled and reused. Simply wash or sterilize the molded material (e.g. via gamma treatment) and re-mold.

Finally, Flexdym has tunable bonding strength, which varies according to the material selected as a substrate. 

POLYSTYRENE (PS)

Strong Bonding, up to several bars.

POLYCARBONATE (PC)

Strong Bonding, up to several bars.

GLASS

Weak Bonding, ranging 500-700 mbar. Best for capillary devices.

POLYDIMETHYLSILOXANE (PDMS)

Weak Bonding.

POLYMETHYLMETACRYLATE (PMMA)

Moderate Bonding.

CYCLIC OLEFIN COPOLYMER (COC)

Strong Bonding, reaching several bars.

CYCLIC OLEFIN POLYMER (COP)

Strong Bonding, reaching several bars.

Top Flexdym Applications Right Now

Cell Culture

Flexdym has lower sorption properties & gas permeability. 

Reversible Seals

Flexdym can bond reversibly to a variety of substrates, acting as a excellent seal on devices.

Eden Materials Flexdym sheets starter pack alternative to PDMS | Eden Tech

Valves

Flexdym has an elongation of 700%, meaning it can stretch to 7 times is original size.

Skin-Interfacing

Flexdym is a pressure sensitive adhesive that naturally sticks to the skin.

Flexdym Application: Bioreactors & Cell Culture

flexdym for cell culture experiements - hugo salmon

1.H. Salmon et al., Engineering Reports 2021, 2. A. McMillian et al., Micromachines 2020

Flexdym has many advantages for bioreactor and cell culture microfluidic applications.

Certified biocompatiblity ISO 10993 parts 4,5,6,10 & 11 and USP Class VI international standards.

Optical transparency, with UV-Vis trasnmittance over 295-800 nm.

Reversible bonding to range of substrates (ideal for switching between open and closed cell culture).

Moderately hydrophobic, but also demonstrates highly stable hydrophilicity with oxygen plasma (1 week to 1 month depending on storage conditions).

Device fabrication in as little as 2 minutes.

Scalable material, also ideal for mass production.

Flexdym Application: Diagnostics

flexdym for point of care diagnostics

E. Roy et al., Lab on a Chip 2015

Flexdym also has advantages for microfluidic diagnostic applications.

Low absorption of DNA targets and primers.

Optical transparency, with UV-Vis trasnmittance over 295-800 nm.

Material cost optimization, ideal for diagnostic cartridges.

Resistance to Fluorinated oil for digital amplification.

Thermostability for thermocycling and enzyme activation.

Flexdym Mechanical Properties.

Flexdym combines properties of thermoplastics and elastomers. This explains it’s elasticity (Young Modulus of 1.15 MPa) and simultaneous ability to be hot embossed. 

Eden Tech Youtube Channel

Videos & tips demonstrating how easy it is to to use all our products! Find step-by-step explanations on a variety of topics including:

Flexdym Bonding
Flexdym Molding
Sublym Program Setup
Epoxym kit steps
and more…

Who Are Flexdym Users?

Flexdym New Material for Academic Microfluidics Prototyping | Eden Tech
Flexdym New Material for Academic Microfluidics Industrial R&D | Eden Tech
Flexdym New Material for R&D biotech start-ups | Eden Tech
Flexdym New Microfabrication material for R&D device fabs | Eden Tech

What Flexdym Users Say...

" We are having a great experience using Flexdym sheets to develop our organ-on-chip technology! The protocol is more user-friendly and less messy than what we were used to with PDMS. You skip all the prep work! No mixing or degassing. Eden also provides great customer service throughout the entire process, making it easier for us to advance towards commercializing our devices. "
CTO Finnadvance Tuan Nguyen
Tuan Nguyen
CTO at Finnadvance
"[...] the Flexdym polymer has become for us an exciting microfluidic medium, allowing us to develop new applications in analytical chemistry as well as cell culture. With original material properties and an excellent capacity for protytping, Eden's materials, instruments and knowledge contributed to develop our autonomy with thermoplastic microfluidics."
Hugo Salmon Tabrizian group, McGill University
Hugo Salmon
McGill University

Eden Materials Flexdym Clients...

Flexdym Brochures & Documents

Flex Users Worldwide

The Flexdym user community is growing quickly and strongly. Today, Eden Tech has clietns all over the world over 4 different continents. We also have 2 distributors in the United States (Flowcell) and China (Youngchip).

Insightful Publications

Eden Tech

Headquarters:
11 Rue de Lourmel 
Paris 75015, France

Client Facing Offices:
4 Rue de Rambervillers
Paris 75012, France

Trademark Flexdym  and Sublym – EU.IP Offices.

Interested in Finding Out More?Sign Up for Our Scientific Product Updates
0
    0
    Your Cart
    Your cart is emptyHomepage

    Are you Interested ? Maybe We Can Help!

    The more we know you, the better we can help!