PELLETS
FLEXDYM BIOCOMPATIBLE MATERIAL
The Flexdym pellets are perfect for the experimented user who has developed a marketable product using this technology and wish to begin mass production or 3D printing.Â
PELLETS
FLEXDYM BIOCOMPATIBLE MATERIAL
The Flexdym pellets are perfect for the experimented user who has developed a marketable product using this technology and wish to begin mass production or 3D printing.Â
Flexdym Pellets - Polymer For Mass Production
Flexdymâ„¢ Pellets – Device Mass Production
The Flexdym pellets is perfect for experimented user who have developed a marketable product using this technology, and wish to begin mass production or 3D printing. Pellets are sold at different prices from weight ranges: 1-10kg, 11-1,000kg, and 1,001-10,000kg. Please select the variation corresponding to the amount you require.
If you are looking for a solution to microfluidics device mass production, our Flexdymâ„¢ pellets may be the perfect material for you.
Microfluidics Scalability Challenges
Microfluidics suffers from a lack of both biocompatible and scalable materials for device mass production. In this domain, academics favor elastomeric materials, such as PDMS (polydimethylsiloxane), for device prototyping. And although PDMS has a relatively simple fabrication protocol, it lacks scalability, and PDMS microfluidic devices must be manually bonded and assembled. This hampers commercialization.
On the other hand, industry experts prefer thermoplastic materials, including COC, COP, PS, or PC. This is due to their scalability and compatibility with mass production processes, e.g. injection molding. However, these materials also harbor drawbacks for biomedical applications. For example, they require bonding treatments with harsh chemical and temperature conditions, that are not ideal for surface functionalization. Additionally, they are expensive to use at prototyping stages – limiting their widespread use.
The Flexdymâ„¢ Solution
To solve this issue, we have created Flexdymâ„¢. Flexdymâ„¢ is a popular alternative to PDMS and specifically created for the scale up of microfluidic biomedical devices, thanks to its compatibility with injection molding and 3D printing. Moreover, Flexdym is ideal for biological applications, because it is certified biocompatible ISO 10993 (parts 4, 5, 6, 10, 11) and UPS Class VI. This demonstrates Flexdymâ„¢’s low toxicity and its ability to be used for medical applications. Other advantages of Flexdymâ„¢ include optical transparency and low molecular sorption, which make Flexdymâ„¢ a top choice for cell culture and diagnostic applications.
Now you can finally use the same material at all scales, from prototyping to mass production of your chips. Flexdym makes commercialization of microfluidic chips easy.
Interested in first testing out the Flexdymâ„¢ polymer? Check out our Flexdymâ„¢ Starter Pack. But if you already have experience with Flexdymâ„¢ but require more development before beginning mass production, you should see our Flexdymâ„¢ Rolls.
And make sure to follow us on LinkedIn and Youtube to get our the lastest Flexdymâ„¢ news!
Weight | N/A |
---|---|
Quantity | 1-10kg, 11-1000kg, 1001-10000kg |
Flexdym Pellets for Mass Production
Eden Tech has created the Flexdym pellet format as a low cost option for mass production. Flexdym pellets are ideal for commonly used injection molding or 3D printing. But they can also be used for small scale production with the help of a classic hot press.
Flexdym Pellets are available per kilo.Â
The pellets can be molded at small scales, suing our Sublym or a hot press, and at large scales using injection molding or 3D printing.
The injection molding process allows Flexdym devices to be mass produced - a key advantage for product development.
A Biocompatible Material that is Scalable.
From Prototyping...
Use Flexdym starter packs or rolls to create chips quickly and easily. Mold Flexdym in 2 minutes using our Sublym machine. The Flexdym protocol length is approx. 15-20 minutes, so you can save time in the lab.
To Mass Production.
The Flexdym pellets are compatible with injection molding machines used in mass production. Now you have the opportunity to turn you technology into a commercial product.
Injection Molding for Mass Production.
NO.
|
PARAMETER
|
VALUE
|
---|---|---|
1
|
Screw Size
|
30mm (circumference)
|
2
|
Injection Speed
|
8cm3/s
|
3
|
Injection Pressure
|
Max 1000bar (700-800bar)
|
4
|
Holding Pressure
|
5bar
|
5
|
Mold Temperature
|
25-30°C
|
6
|
Cooling Time
|
12s
|
BARREL TEMPERATURE (°C)
|
|||
---|---|---|---|
Zone 1
|
Zone 2
|
Zone 3
|
Nozzle
|
235
|
250
|
255
|
255
|
Gas Permeability Results for Flexdym
PERMEABILITY
|
FLEXDYM RESULTS
|
---|---|
Oxygen
|
7.86 Barrer
|
Carbon dioxide
|
15.99 Barrer
|
*Results for 2 mm thickness sheet in test conditions 23°C, 50% RH
Resistance to Solvents
CHEMICAL
|
RESISTANCE
|
---|---|
Acids
|
R
|
Bases
|
R
|
Fluorinated Oils
|
R
|
Methanol/ Ethanol
|
R
|
Carboxylic Acid
|
Swell
|
Hydrocarbons
|
NR
|
Oil
|
Swell
|
Versatility: Flexdym Bonding Strength
Flexdym combines the best properties of elastomers, like PDMS, and thermoplastics, like COC, polystyrene or polycarbonate. Flexdym acheives this through its block co-polymer structure composed of styrenic hard blocks and ethylene-butylene soft blocks, which allow it to remain soft, yet compatible with hot embossing.
Flexdym acts as a pressure sensitive adhesive, bonding with a selection of substrates through conformal contact. Flexdym bonding can be accomplished through manual lamination using a roller, or standardised through the use of a press.
Flexdym can be recycled and reused. Simply wash or sterilize the molded material (e.g. via gamma treatment) and re-mold.
Finally, Flexdym has tunable bonding strength, which varies according to the material selected as a substrate.Â
POLYMER
|
GRADE
|
COMPANY
|
THICKNESS (mm)
|
---|---|---|---|
Polystyrene (PS)
|
Crystal Polystyrene
|
Eloise
|
1
|
Polycarbonate (PC)
|
Lexan *8040
|
Sabic
|
0.175
|
Polyimide (PI)
|
Kapton HN
|
Fralock
|
0.125
|
Polyimide (PI)
|
Crilex
|
Fralock
|
1
|
PMMA
|
Acrylite H12
|
Eloise
|
1
|
COC
|
Europlex COC 99304
|
Topas
|
1
|
COP
|
ZenorFilm TM
|
-
|
0.1
|
BONDING STRENGTHS TESTED
|
|
---|---|
Flexdym
|
8 bars
|
Glass
|
700 mbars
|
COC
|
2 bars
|
COP
|
2 bars
|
PC
|
2 bars
|
PMMA
|
2 bars
|
Polyimide
|
2 bars
|
Flexdym 3D Printing Sneak Peek
Create Flexdym Microfluidic Devices In Minutes
Eden Tech Youtube Channel
Videos & tips demonstrating how easy it is to to use all our products! Find step-by-step explanations on a variety of topics including:
Flexdym Bonding
Flexdym Molding
Flexdym 3D Printing
Sublym for ThermoplasticsÂ
Sublym Program Setup
Epoxym kit steps
and more…
Eden Tech Youtube Channel
Videos & tips demonstrating how easy it is to to use all our products! Find step-by-step explanations on a variety of topics including:
Flexdym Bonding
Flexdym Molding
Flexdym 3D Printing
Sublym for ThermoplasticsÂ
Sublym Program Setup
Epoxym kit steps
and more…
Step-By-Step: Flexdym Devices
01
Mold the Flexdym pellets using hot embossing or injection molding
02
Unmold Flexdym
03
Create inlet/outlet ports
04
Bond Flexdym to substrate
Versatility: Flexdym Bonding Strength
Flexdym combines the best properties of elastomers, like PDMS, and thermoplastics, like COC, polystyrene or polycarbonate. Flexdym acheives this through its block co-polymer structure composed of styrenic hard blocks and ethylene-butylene soft blocks, which allow it to remain soft, yet compatible with hot embossing.
Flexdym acts as a pressure sensitive adhesive, bonding with a selection of substrates through conformal contact. Flexdym bonding can be accomplished through manual lamination using a roller, or standardised through the use of a press.
Flexdym can be recycled and reused. Simply wash or sterilize the molded material (e.g. via gamma treatment) and re-mold.
Finally, Flexdym has tunable bonding strength, which varies according to the material selected as a substrate.Â
POLYSTYRENE (PS)
Strong Bonding, up to several bars.
POLYCARBONATE (PC)
Strong Bonding, up to several bars.
GLASS
Weak Bonding, ranging 500-700 mbar. Best for capillary devices.
POLYDIMETHYLSILOXANE (PDMS)
Weak Bonding.
POLYMETHYLMETACRYLATE (PMMA)
Moderate Bonding.
CYCLIC OLEFIN COPOLYMER (COC)
Strong Bonding, reaching several bars.
CYCLIC OLEFIN POLYMER (COP)
Strong Bonding, reaching several bars.
Top Flexdym Applications Right Now.
Cell Culture
Flexdym has lower sorption properties & gas permeability.Â
Reversible Seals
Flexdym can bond reversibly to a variety of substrates, acting as a excellent seal on devices.
Valves
Flexdym has an elongation of 700%, meaning it can stretch to 7 times is original size.
Skin-Interfacing
Flexdym is a pressure sensitive adhesive that naturally sticks to the skin.
Flexdym Pricing
Flexdym’s pricing is comparable to other widely used microfabrication materials, with the added advantages of being:
Biocompatible
Transparent
Scalable
User-Friendly
Flexdym Mechanical Properties.
Flexdym combines properties of thermoplastics and elastomers. This explains it’s elasticity (Young Modulus of 1.15 MPa) and simultaneous ability to be hot embossed.Â
Flexdym Application: Cell Culture
1.H. Salmon et al., Engineering Reports 2021, 2. A. McMillian et al., Micromachines 2020
Flexdym has many advantages for bioreactor and cell culture microfluidic applications.
Certified biocompatiblity ISO 10993 parts 4,5,6,10 & 11 and USP Class VI international standards.
Optical transparency, with UV-Vis trasnmittance over 295-800 nm.
Reversible bonding to range of substrates (ideal for switching between open and closed cell culture).
Moderately hydrophobic, but also demonstrates highly stable hydrophilicity with oxygen plasma (1 week to 1 month depending on storage conditions).
Device fabrication in as little as 2 minutes.
Scalable material, also ideal for mass production.
Flexdym Application: Diagnostics
Flexdym also has advantages for microfluidic diagnostic applications.
Low absorption of DNA targets and primers.
Optical transparency, with UV-Vis trasnmittance over 295-800 nm.
Material cost optimization, ideal for diagnostic cartridges.
Resistance to Fluorinated oil for digital amplification.
Thermostability for thermocycling and enzyme activation.
E. Roy et al., Lab on a Chip 2015
Flexdym Brochures & Documents
Flexdym is our original and patented material, developed by our CEO Emmanuel Roy. Unlike other materials used in microfluidics device fabrication, Flexdym is the first material created specifically for microfluidics biomedical applications. Our Sublym hot embossing machine was then created to render device replication fast and easy. It is compact, user-friendly and affordable. Finally, our Epoxym kit produces robust mold replicas from silicon wafer molds. For more information on any of these products, check out our brochures below.
Who are Flexdym Users?
Review: Flexdym Polymer
Review: Flexdym Polymer
Review: Flexdym Polymer
Eden Materials Flexdym Clients...
Flex Users Worldwide
The Flexdym user community is growing quickly and strongly. Today, Eden Tech has clietns all over the world over 4 different continents. We also have 2 distributors in the United States (Flowcell) and China (Youngchip).
Scientific Publications
Flexdym users worldwide are publishing their microfluidics research in top peer reviewed journals including, Nature, Advanced Materials, Analytical Chemistry, Lab on Chip and more. The topics also vary from cell culture and point of care diagnostics, to flexible electronics, wearable devices and micromixers. For a copy of our publications contatc us below!
Eden Tech
Headquarters:
11 Rue de Lourmel
Paris 75015, France
Client Facing Offices:
4 Rue de Rambervillers
Paris 75012, France
 The Licensee shall also mark all Products with labels containing the following language: Thermoplastic materials, Flexdym, Flexaspin, Fluoroflex, are sold under license to US patents 9,238,346 and 10,369,566 and CA patent 2,681,897 from the National Research Council Canada. Rights to use these products are limited to research uses only and are not to be used for any other purpose, such as but not limited to, commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of unauthorized applications. No other rights are conveyed. Inquiry into the availability of a license to broader rights or the use of these thermoplastic materials for commercial purposes should be directed to National Research Council Canada. Purchase of these products does not grant rights to (1) offer the products or any derivatives thereof for resale; or (2) to distribute or transfer the products or any derivative thereof to third parties.
Â
Trademark Flexdym and Sublym – EU.IP Offices.