Eden Materials

Flexdym Pellets - Polymer For Mass Production

The Flexdym pellets is perfect for experimented user who have developed a marketable product using this technology, and wish to begin mass production or 3D printing. Pellets are sold at different prices from weight ranges: 1-10kg, 11-1,000kg, and 1,001-10,000kg. Please select the variation corresponding to the amount you require.

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If you are looking for a solution to microfluidics device mass production, our Flexdym™ pellets may be the perfect material for you.

Microfluidics Scalability Challenges

Microfluidics suffers from a lack of both biocompatible and scalable materials for device mass production. In this domain, academics favor elastomeric materials, such as PDMS (polydimethylsiloxane), for device prototyping. And although PDMS has a relatively simple fabrication protocol, it lacks scalability, and PDMS microfluidic devices must be manually bonded and assembled. This hampers commercialization.

On the other hand, industry experts prefer thermoplastic materials, including COC, COP, PS, or PC. This is due to their scalability and compatibility with mass production processes, e.g. injection molding. However, these materials also harbor drawbacks for biomedical applications. For example, they require bonding treatments with harsh chemical and temperature conditions, that are not ideal for surface functionalization. Additionally, they are expensive to use at prototyping stages – limiting their widespread use.

The Flexdym™ Solution

To solve this issue, we have created Flexdym™. Flexdym™ is a popular alternative to PDMS and specifically created for the scale up of microfluidic biomedical devices, thanks to its compatibility with injection molding and 3D printing. Moreover, Flexdym is ideal for biological applications, because it is certified biocompatible ISO 10993 (parts 4, 5, 6, 10, 11) and UPS Class VI. This demonstrates Flexdym™’s low toxicity and its ability to be used for medical applications. Other advantages of Flexdym™ include optical transparency and low molecular sorption, which make Flexdym™ a top choice for cell culture and diagnostic applications.

Now you can finally use the same material at all scales, from prototyping to mass production of your chips. Flexdym makes commercialization of microfluidic chips easy.

Interested in first testing out the Flexdym™ polymer? Check out our Flexdym™ Starter Pack. But if you already have experience with Flexdym™ but require more development before beginning mass production, you should see our Flexdym™ Rolls.

And make sure to follow us on LinkedIn and Youtube to get our the lastest Flexdym™ news!

Weight N/A
Quantity

1-10kg, 11-1000kg, 1001-10000kg

Flexdym Pellets for Mass Production

Eden Tech has created the Flexdym pellet format as a low cost option for mass production. Flexdym pellets are ideal for commonly used injection molding or 3D printing. But they can also be used for small scale production with the help of a classic hot press.

flexdym pellets logo orange | Eden Tech

Flexdym Pellets are available per kilo. 

Flexdym Pellets Injection sketch orange | Eden Tech

The pellets can be molded at small scales, suing our Sublym or a hot press, and at large scales using injection molding or 3D printing.

Flexdym microfluidic device image orangeFlexdym roll orange | Eden Tech

The injection molding process allows Flexdym devices to be mass produced - a key advantage for product development.

A Biocompatible Material that is Scalable.

Flexdym scaling layout - Eden Tech

From Prototyping...

Use Flexdym starter packs or rolls to create chips quickly and easily. Mold Flexdym in 2 minutes using our Sublym machine. The Flexdym protocol length is approx. 15-20 minutes, so you can save time in the lab.

To Mass Production.

The Flexdym pellets are compatible with injection molding machines used in mass production. Now you have the opportunity to turn you technology into a commercial product.

Injection Molding for Mass Production.

Flexdym Pellets for injection molding and mass production | Eden Tech
NO.
PARAMETER
VALUE
1
Screw Size
30mm (circumference)
2
Injection Speed
8cm3/s
3
Injection Pressure
Max 1000bar (700-800bar)
4
Holding Pressure
5bar
5
Mold Temperature
25-30°C
6
Cooling Time
12s
BARREL TEMPERATURE (°C)
Zone 1
Zone 2
Zone 3
Nozzle
235
250
255
255

Gas Permeability Results for Flexdym

PERMEABILITY
FLEXDYM RESULTS
Oxygen
7.86 Barrer
Carbon dioxide
15.99 Barrer
*Results for 2 mm thickness sheet in test conditions 23°C, 50% RH

Resistance to Solvents

CHEMICAL
RESISTANCE
Acids
R
Bases
R
Fluorinated Oils
R
Methanol/ Ethanol
R
Carboxylic Acid
Swell
Hydrocarbons
NR
Oil
Swell

Versatility: Flexdym Bonding Strength

Flexdym combines the best properties of elastomers, like PDMS, and thermoplastics, like COC, polystyrene or polycarbonate. Flexdym acheives this through its block co-polymer structure composed of styrenic hard blocks and ethylene-butylene soft blocks, which allow it to remain soft, yet compatible with hot embossing.

Flexdym acts as a pressure sensitive adhesive, bonding with a selection of substrates through conformal contact. Flexdym bonding can be accomplished through manual lamination using a roller, or standardised through the use of a press.

Flexdym can be recycled and reused. Simply wash or sterilize the molded material (e.g. via gamma treatment) and re-mold.

Finally, Flexdym has tunable bonding strength, which varies according to the material selected as a substrate. 

POLYMER
GRADE
COMPANY
THICKNESS (mm)
Polystyrene (PS)
Crystal Polystyrene
Eloise
1
Polycarbonate (PC)
Lexan *8040
Sabic
0.175
Polyimide (PI)
Kapton HN
Fralock
0.125
Polyimide (PI)
Crilex
Fralock
1
PMMA
Acrylite H12
Eloise
1
COC
Europlex COC 99304
Topas
1
COP
ZenorFilm TM
-
0.1
BONDING STRENGTHS TESTED
Flexdym
8 bars
Glass
700 mbars
COC
2 bars
COP
2 bars
PC
2 bars
PMMA
2 bars
Polyimide
2 bars

Flexdym 3D Printing Sneak Peek

Create Flexdym Microfluidic Devices In Minutes

Eden Tech Youtube Channel

Videos & tips demonstrating how easy it is to to use all our products! Find step-by-step explanations on a variety of topics including:

Flexdym Bonding
Flexdym Molding
Flexdym 3D Printing
Sublym for Thermoplastics 
Sublym Program Setup
Epoxym kit steps
and more…

Step-By-Step:
Flexdym Devices

01

flexdym pellets logo orange | Eden Tech

Mold the Flexdym pellets using hot embossing or injection molding

02

Mold Flexdym Sheet Sketch orange | Eden Tech

Unmold Flexdym

03

Flexdym Create Inlets and Outlets Sketch Orange | Eden Tech

Create inlet/outlet ports

04

Flexdym Device Ready Sketch Orange | Eden Tech

Bond Flexdym to substrate

Versatility: Flexdym Bonding Strength

Flexdym combines the best properties of elastomers, like PDMS, and thermoplastics, like COC, polystyrene or polycarbonate. Flexdym acheives this through its block co-polymer structure composed of styrenic hard blocks and ethylene-butylene soft blocks, which allow it to remain soft, yet compatible with hot embossing.

Flexdym acts as a pressure sensitive adhesive, bonding with a selection of substrates through conformal contact. Flexdym bonding can be accomplished through manual lamination using a roller, or standardised through the use of a press.

Flexdym can be recycled and reused. Simply wash or sterilize the molded material (e.g. via gamma treatment) and re-mold.

Finally, Flexdym has tunable bonding strength, which varies according to the material selected as a substrate. 

POLYSTYRENE (PS)

Strong Bonding, up to several bars.

POLYCARBONATE (PC)

Strong Bonding, up to several bars.

GLASS

Weak Bonding, ranging 500-700 mbar. Best for capillary devices.

POLYDIMETHYLSILOXANE (PDMS)

Weak Bonding.

POLYMETHYLMETACRYLATE (PMMA)

Moderate Bonding.

CYCLIC OLEFIN COPOLYMER (COC)

Strong Bonding, reaching several bars.

CYCLIC OLEFIN POLYMER (COP)

Strong Bonding, reaching several bars.

Top Flexdym Applications Right Now.

Cell Culture

Flexdym has lower sorption properties & gas permeability. 

Reversible Seals

Flexdym can bond reversibly to a variety of substrates, acting as a excellent seal on devices.

Eden Materials Flexdym sheets starter pack alternative to PDMS | Eden Tech

Valves

Flexdym has an elongation of 700%, meaning it can stretch to 7 times is original size.

Skin-Interfacing

Flexdym is a pressure sensitive adhesive that naturally sticks to the skin.

Flexdym Pricing

Flexdym’s pricing is comparable to other widely used microfabrication materials, with the added advantages of being:

Biocompatible

Transparent

Scalable

User-Friendly

Flexdym Mechanical Properties.

Flexdym combines properties of thermoplastics and elastomers. This explains it’s elasticity (Young Modulus of 1.15 MPa) and simultaneous ability to be hot embossed. 

Flexdym Application: Cell Culture

flexdym for cell culture experiements - hugo salmon

1.H. Salmon et al., Engineering Reports 2021, 2. A. McMillian et al., Micromachines 2020

Flexdym has many advantages for bioreactor and cell culture microfluidic applications.

Certified biocompatiblity ISO 10993 parts 4,5,6,10 & 11 and USP Class VI international standards.

Optical transparency, with UV-Vis trasnmittance over 295-800 nm.

Reversible bonding to range of substrates (ideal for switching between open and closed cell culture).

Moderately hydrophobic, but also demonstrates highly stable hydrophilicity with oxygen plasma (1 week to 1 month depending on storage conditions).

Device fabrication in as little as 2 minutes.

Scalable material, also ideal for mass production.

Flexdym Application: Diagnostics

Flexdym also has advantages for microfluidic diagnostic applications.

Low absorption of DNA targets and primers.

Optical transparency, with UV-Vis trasnmittance over 295-800 nm.

Material cost optimization, ideal for diagnostic cartridges.

Resistance to Fluorinated oil for digital amplification.

Thermostability for thermocycling and enzyme activation.

flexdym for point of care diagnostics PCR chip - emmanuel roy

E. Roy et al., Lab on a Chip 2015

Flexdym Brochures & Documents

Flexdym is our original and patented material, developed by our CEO Emmanuel Roy. Unlike other materials used in microfluidics device fabrication, Flexdym is the first material created specifically for microfluidics biomedical applications. Our Sublym hot embossing machine was then created to render device replication fast and easy. It is compact, user-friendly and affordable. Finally, our Epoxym kit produces robust mold replicas from silicon wafer molds. For more information on any of these products, check out our brochures below.

    Who are Flexdym Users?

    Flexdym New Material for Academic Microfluidics Prototyping | Eden Tech
    Flexdym New Material for Academic Microfluidics Industrial R&D | Eden Tech
    Flexdym New Material for R&D biotech start-ups | Eden Tech
    Flexdym New Microfabrication material for R&D device fabs | Eden Tech

    What Flexdym Users Say...

    " We are having a great experience using Flexdym sheets to develop our organ-on-chip technology! The protocol is more user-friendly and less messy than what we were used to with PDMS. You skip all the prep work! No mixing or degassing. Eden also provides great customer service throughout the entire process, making it easier for us to advance towards commercializing our devices. "
    CTO Finnadvance Tuan Nguyen
    Tuan Nguyen
    CTO at Finnadvance
    "[...] the Flexdym polymer has become for us an exciting microfluidic medium, allowing us to develop new applications in analytical chemistry as well as cell culture. With original material properties and an excellent capacity for protytping, Eden's materials, instruments and knowledge contributed to develop our autonomy with thermoplastic microfluidics."
    Hugo Salmon Tabrizian group, McGill University
    Hugo Salmon
    McGill University

    Eden Materials Flexdym Clients...

    Flex Users Worldwide

    The Flexdym user community is growing quickly and strongly. Today, Eden Tech has clietns all over the world over 4 different continents. We also have 2 distributors in the United States (Flowcell) and China (Youngchip).

    Eden Tech - Flexdym Users Worldwide

    Scientific Publications

    Flexdym users worldwide are publishing their microfluidics research in top peer reviewed journals including, Nature, Advanced Materials, Analytical Chemistry, Lab on Chip and more. The topics also vary from cell culture and point of care diagnostics, to flexible electronics, wearable devices and micromixers. For a copy of our publications contatc us below!

      Eden Tech

      Headquarters:
      11 Rue de Lourmel 
      Paris 75015, France

      Client Facing Offices:
      4 Rue de Rambervillers
      Paris 75012, France

      Trademark Flexdym  and Sublym – EU.IP Offices.

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