Organ-on-a-chip

Cell Alignment Strategies for Organ-on-Chip Technologies

Cell Culture / /

The functionalities of organs and tissues are tightly linked with their structure and, the organisation of constituent cells. Cues from the surrounding extracellular matrix direct the orientation and alignment of cells with respect to one another through contact guidance [1]. This microenvironment is crucial in dictating cell fate; affecting morphology, proliferation, differentiation, response to stimuli, […]

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Human on a Chip Focus: Vasculature Systems on a Chip

Organ-on-chips, Review / /

The vasculature is the main structure of the circulatory system through which nutrients, oxygen and biological secretions are transported throughout the body. This large network has specific structures regarding their functions. Among all the vital ones, our vasculature carries blood from the largest arteries towards the tiniest capillaries. The functional disorders of the vascular system

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Human on a Chip Focus: Digestive System on a Chip

Organ-on-chips / /

The human digestive system is a powerful machine able to transform organic matter into energy, all while filtering out any threatening and unnecessary elements. This system is however not infallible; malfunctions can occur and pathogens can sometimes get past the screening process. To investigate these events and find a treatment or cure, researchers and pharmaceutical

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