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Cell Alignment Strategies for Organ-on-Chip Technologies

The functionalities of organs and tissues are tightly linked with their structure and, the organisation of constituent cells. Cues from the surrounding extracellular matrix direct the orientation and alignment of cells with respect to one another through contact guidance [1]. This microenvironment is crucial in dictating cell fate; affecting morphology, proliferation, differentiation, response to stimuli, …

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SEBS Polymers for Microfluidic Biotech Devices - Cover

Polymers for Microfluidic Devices: Surface Functionalization

Modern Point-of-Care diagnostic devices rely on microfluidic technology to analyze the smallest amount of fluid, for the highest measurement precision possible. To do so, the microfluidic devices require powerful tools to detect and measure targeted elements (e.g., pathogens). This can be achieved by coating the microfluidic channel walls with the appropriate molecules (e.g., antibodies) to …

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Human on a Chip Focus: Digestive System on a Chip banner

Human on a Chip Focus: Digestive System on a Chip

The human digestive system is a powerful machine able to transform organic matter into energy, all while filtering out any threatening and unnecessary elements. This system is however not infallible; malfunctions can occur and pathogens can sometimes get past the screening process. To investigate these events and find a treatment or cure, researchers and pharmaceutical …

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