Why You Should Think Twice Before Using PDMS in Microfluidics What is PDMS and Why It’s Popular PDMS (Polydimethylsiloxane) has been the go-to material in academic microfluidics. Its low cost, optical clarity, and ease of prototyping via soft lithography made it the standard in university labs. But times have changed. In industrial, diagnostic, and even […]
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Microfluidics in 2025: Applications, Trends & How It Work What Is Microfluidics? Microfluidics is the interdisciplinary science of manipulating small volumes of fluids,typically microliters to picoliters, within micro-scale channels (less than 1 mm wide). This technology integrates principles from physics, chemistry, biology, and engineering to create systems that can mix, sort, and analyze fluids with precision.
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Reversible Bonding in Microfluidics: A PDMS Alternative In the evolving field of microfluidics, the demand for reusable, biocompatible, and easy-to-access devices is growing rapidly. Traditional materials such as polydimethylsiloxane (PDMS), while widely used, show major limitations. Especially when it comes to reversible bonding and small molecule adsorption. A recent study by Moreau et al. introduces
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Sublym Hot embossing + Bonding 2-in-1 machine Application Note Introduction The evolution of the microfluidics field demands fabrication methods that are both efficient and cost-effective. The Sublym machine, which we can call a “2-in-1 machine”, facilitates the efficient hot embossing and bonding of advanced Flexdym materials with other classical thermoplastics (COC, PMMA, PS…), streamlining the
The Potential of 3D Printing using 2PP technology in Skeletal Muscle Engineering – Application Note Introduction 3D printing has revolutionized various fields by enabling precise and customizable fabrication of complex structures. In the context of skeletal muscle engineering, 2-photon polymerization (2PP)-based 3D printing offers significant potential to overcome existing limitations in scaffold and microfluidic design.
Room Temperature and Equipment-Free Microfluidic Device assembly & Bonding – Application Note Introduction The fabrication of microfluidic devices, essential for numerous applications in biomedical, pharmaceutical, and chemical industries, faces significant challenges, primarily related to bonding. Ensuring robust, and reliable bonding without the need for expensive cleanroom facilities is crucial for the widespread adoption of microfluidic
Optimizing Microfluidics: The Advantages of Piercing Inlets and Outlets Directly During Fast Flexdym Moulding Microfluidic devices have become indispensable in a variety of fields, from medical diagnostics to chemical synthesis. The demand for more efficient, precise, and scalable manufacturing processes has driven innovation in the way these devices are produced. This recent report outlines a
Use of Flexdym in Skin-Interfaced Sweat Microfluidic Devices Case Study Overview This case study highlights the innovative application of Flexdym. A thermoplastic elastomer (TPS), in developing skin-interfaced sweat microfluidic devices. Flexdym was selected for its unique properties that enhance the functionality and reliability of these devices. Particularly in the context of wireless, skin-interfaced electronic systems.
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Exploring the Potential of Flexdym in Fabricating MultiU-Int Microfluidic Chips. For Deciphering the Immunopathogenesis of Inflammatory Bowel Disease (IBD) – Case Study The intricate immunopathogenesis of Inflammatory Bowel Disease (IBD) necessitates advanced experimental models to decipher its complex mechanisms. Recent advancements in microfluidic technologies, particularly in the development of intestine-on-chip systems, offer promising avenues for
The versatility and benefits of microfluidics can be integrated for the conception and development of devices for point of care diagnostics.
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