Eden Materials

Microfluidic design – Step by step

Introduction to Microfluidics and Microfluidic Design Microfluidics represents a cutting-edge domain focused on the control of fluids at a microscopic level. It finds extensive application in areas such as medical diagnostics, chemical analysis, and drug discovery research. Microfluidic design can be challenging for researchers, PhDs, or engineers. A standard microfluidic device has channels and chambers. […]

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Cell Alignment Strategies for Organ-on-Chip Technologies

The functionalities of organs and tissues are tightly linked with their structure and, the organisation of constituent cells. Cues from the surrounding extracellular matrix direct the orientation and alignment of cells with respect to one another through contact guidance [1]. This microenvironment is crucial in dictating cell fate; affecting morphology, proliferation, differentiation, response to stimuli,

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Polymers for Microfluidic Devices: Surface Functionalization

Modern Point-of-Care diagnostic devices rely on microfluidic technology to analyze the smallest amount of fluid, for the highest measurement precision possible. To do so, the microfluidic devices require powerful tools to detect and measure targeted elements (e.g., pathogens). This can be achieved by coating the microfluidic channel walls with the appropriate molecules (e.g., antibodies) to

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Human on a Chip Focus: Vasculature Systems on a Chip

Digestive System On a Chip The vasculature is the main structure of the circulatory system through which nutrients, oxygen and biological secretions are transported throughout the body. This large network has specific structures regarding their functions. Among all the vital ones, our vasculature carries blood from the largest arteries towards the tiniest capillaries. The functional

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Human on a Chip Focus: Digestive System on a Chip

The human digestive system is a powerful machine able to transform organic matter into energy, all while filtering out any threatening and unnecessary elements. This system is however not infallible; malfunctions can occur and pathogens can sometimes get past the screening process. To investigate these events and find a treatment or cure, researchers and pharmaceutical

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Four Methods of 3D Cell Culture in Microfluidic Devices

Recently, microfluidics and 3D cell culture technologies have merged, to increase the potential of in vitro modeling, in order to get even closer to Nature. The successful control of the cellular environment thanks to microfluidics in a 3D cell culture environment allows the study at the single-cell scale with mechanical control of cell shape, physicochemical

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Organ-on-Chip Technologies : Standing Out to French Politicians

Last week, we had the pleasure of welcoming Senator Arnaud Bazin and his collaborator, Madame Agnes Borie, at our Eden Tech offices in Paris to discuss the role of microfluidics as a tool for medical research. Senator Bazin, has extensive political experience in France, acting as Senator, following his role as President of the general

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From Organ-on-Chips to Body-on-a-Chip

With the help of microfluidics, cell culture is taking the next steps with Organ-on-Chips technology. To highlight these incredible milestones, here we discuss a recent Nature review by Tagle et al.[i], members of the National Center for advancing Translational Sciences; We focus on the benefits of the field, discuss its challenges, and explain how Eden Tech can

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