Cell Culture

Learn about our innovative microfluidic solutions for cell culture. These resources provide valuable information on improving experimental control, efficiency, and reproducibility in biological research.

Organ-on-chip design

Organ-on-Chip Design: Materials, Challenges, and a New Approach to Accelerate Innovation

How to Master Organ-on-Chip Design: Tools, Methods & Materials Introduction to Organ-On-Chip Organ-on-Chip (OoC) systems are transforming biomedical research by enabling more physiologically relevant models than traditional 2D cell cultures and animal testing. These microengineered systems integrate microfluidics, tissue engineering, and cell biology to simulate human organ functions in vitro. As the field advances, robust […]

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3D Cell Culture Breakthrough with Harvestable Microvessels

3D Cell Culture Breakthrough: Scalable Vascularized Tissues Using Flexdym™ (2024 Study) What Is 3D Cell Culture? 3D cell culture is a technique that grows cells in three dimensions to better replicate in vivo tissue environments. It is now essential for applications in tissue engineering, drug screening, and regenerative medicine, offering more accurate physiological models than

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Reversible Bonding in Microfluidics: A PDMS Alternative

Reversible Bonding in Microfluidics: A PDMS Alternative In the evolving field of microfluidics, the demand for reusable, biocompatible, and easy-to-access devices is growing rapidly. Traditional materials such as polydimethylsiloxane (PDMS), while widely used, show major limitations. Especially when it comes to reversible bonding and small molecule adsorption. A recent study by Moreau et al. introduces

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Microfluidic Cell Culture: Alternative to PDMS and microfluidic design

Microfluidic Cell Culture: Alternative to PDMS and Microfluidic Design Introduction Microfluidic cell culture has emerged as a powerful tool in the biomedical and pharmaceutical fields. By integrating cell culture into microfluidic devices, researchers can better mimic physiological conditions, control environmental factors, and conduct high-throughput screenings in a much more efficient and reproducible manner. This blog

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Fabricating MultiU-Int Microfluidic Chips

Exploring the Potential of Flexdym in Fabricating MultiU-Int Microfluidic Chips for Deciphering the Immunopathogenesis of Inflammatory Bowel Disease (IBD)

Exploring the Potential of Flexdym in Fabricating MultiU-Int Microfluidic Chips. For Deciphering the Immunopathogenesis of Inflammatory Bowel Disease (IBD) – Case Study The intricate immunopathogenesis of Inflammatory Bowel Disease (IBD) necessitates advanced experimental models to decipher its complex mechanisms. Recent advancements in microfluidic technologies, particularly in the development of intestine-on-chip systems, offer promising avenues for

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Cell Alignment Strategies for Organ-on-Chip Technologies

Cell Alignment Strategies for Organ-on-Chip Technologies The functionalities of organs and tissues are tightly linked with their structure and, the organisation of constituent cells. Cues from the surrounding extracellular matrix direct the orientation and alignment of cells with respect to one another through contact guidance [1]. This microenvironment is crucial in dictating cell fate; affecting

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Four Methods of 3D Cell Culture in Microfluidic Devices

3D Cell culture & Microfluidics Recently, microfluidics and 3D cell culture technologies have merged, to increase the potential of in vitro modeling, in order to get even closer to Nature. The successful control of the cellular environment thanks to microfluidics in a 3D cell culture environment allows the study at the single-cell scale with mechanical

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The Advantages of Cell Culture Devices & Flexdym for Low-Cost Fabrication

Established Methods of Cell Culture Cell culture is a set of biological techniques used to grow cells outside their original in vivo environment, for the purpose of scientific experimentation. It is widely used for in vitro testing in biomedical science to study animal models. However, a great challenge in cell culture techniques is the mimicking

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