Microfluidics

Microfluidics organ-on-chip

Why You Should Think Twice Before Using PDMS in Microfluidic

Why You Should Think Twice Before Using PDMS in Microfluidic PDMS (Polydimethylsiloxane) has been the go-to material in academic microfluidics. Its low cost, optical clarity, and ease of prototyping via soft lithography made it the standard in university labs. But times have changed. In industrial, diagnostic, and even biological applications, PDMS is increasingly seen as […]

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Organ-On-Chip design

Organ-on-Chip Design: Materials, Challenges, and a New Approach to Accelerate Innovation

Organ-on-Chip Design: Principles, Challenges, and Emerging Tools Organ-on-Chip (OoC) systems are reshaping the landscape of biomedical research by offering more physiologically accurate models than traditional 2D cultures and animal testing. These microengineered platforms simulate the structure and function of human organs using microfluidics, tissue engineering, and cell biology. As researchers and engineers seek to design

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Flexdym Microfluidic chips

Microfluidics in 2025: Applications, Trends & How It Work

Microfluidics in 2025: Applications, Trends & How It Work What Is Microfluidics? Microfluidics is the interdisciplinary science of manipulating small volumes of fluids,typically microliters to picoliters, within micro-scale channels (less than 1 mm wide). This technology integrates principles from physics, chemistry, biology, and engineering to create systems that can mix, sort, and analyze fluids with precision.

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Reversible Bonding in Microfluidics: A PDMS Alternative

Reversible Bonding in Microfluidics: A PDMS Alternative In the evolving field of microfluidics, the demand for reusable, biocompatible, and easy-to-access devices is growing rapidly. Traditional materials such as polydimethylsiloxane (PDMS), while widely used, show major limitations. Especially when it comes to reversible bonding and small molecule adsorption. A recent study by Moreau et al. introduces

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Droplet-Based Microfluidics: A Design Guideline

Droplet-Based Microfluidics: A Design Guideline Introduction Introduction Droplet-based microfluidics has emerged as a powerful tool for applications in biotechnology, chemistry, and material sciences. By leveraging the ability to generate and manipulate discrete droplets in immiscible phases, this technique offers high throughput, precise control over reaction conditions, and minimal sample consumption. It’s important to highlight that

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3D Printing with 2PP Technology

The Potential of 3D Printing using 2PP technology in Skeletal Muscle Engineering Application Note

The Potential of 3D Printing using 2PP technology in Skeletal Muscle Engineering – Application Note Introduction 3D printing has revolutionized various fields by enabling precise and customizable fabrication of complex structures. In the context of skeletal muscle engineering, 2-photon polymerization (2PP)-based 3D printing offers significant potential to overcome existing limitations in scaffold and microfluidic design.

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Microfluidic Device

Room Temperature and Equipment-Free Microfluidic Device assembly & Bonding Application Note

Room Temperature and Equipment-Free Microfluidic Device assembly & Bonding – Application Note Introduction The fabrication of microfluidic devices, essential for numerous applications in biomedical, pharmaceutical, and chemical industries, faces significant challenges, primarily related to bonding. Ensuring robust, and reliable bonding without the need for expensive cleanroom facilities is crucial for the widespread adoption of microfluidic

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Microfluidics

Optimizing Microfluidics: The Advantages of Piercing Inlets and Outlets Directly During Fast Flexdym Moulding Application Note

Optimizing Microfluidics: The Advantages of Piercing Inlets and Outlets Directly During Fast Flexdym Moulding Microfluidic devices have become indispensable in a variety of fields, from medical diagnostics to chemical synthesis. The demand for more efficient, precise, and scalable manufacturing processes has driven innovation in the way these devices are produced. This recent report outlines a

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Flexdym in Skin-Interfaced Sweat Microfluidic Devices

Use of Flexdym in Skin-Interfaced Sweat Microfluidic Devices – Case Study

Use of Flexdym in Skin-Interfaced Sweat Microfluidic Devices Case Study Overview This case study highlights the innovative application of Flexdym. A thermoplastic elastomer (TPS), in developing skin-interfaced sweat microfluidic devices. Flexdym was selected for its unique properties that enhance the functionality and reliability of these devices. Particularly in the context of wireless, skin-interfaced electronic systems.

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Fabricating MultiU-Int Microfluidic Chips

Exploring the Potential of Flexdym in Fabricating MultiU-Int Microfluidic Chips for Deciphering the Immunopathogenesis of Inflammatory Bowel Disease (IBD)

Exploring the Potential of Flexdym in Fabricating MultiU-Int Microfluidic Chips. For Deciphering the Immunopathogenesis of Inflammatory Bowel Disease (IBD) – Case Study The intricate immunopathogenesis of Inflammatory Bowel Disease (IBD) necessitates advanced experimental models to decipher its complex mechanisms. Recent advancements in microfluidic technologies, particularly in the development of intestine-on-chip systems, offer promising avenues for

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